AGFG1

AGFG1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2D9L, 2OLM, 2VX8
Dynodwyr
Cyfenwau	AGFG1, HRB, RAB, RIP, ArfGAP with FG repeats 1
Dynodwyr allanol	OMIM: 600862 HomoloGene: 37929 GeneCards: AGFG1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • metal ion binding • GO:0001948, GO:0016582 protein binding • RNA binding Cydrannau o'r gell • cell projection • intracellular membrane-bounded organelle • nuclear pore • neuronal cell body • GO:0016023 cytoplasmic vesicle • cnewyllyn cell • cytosol Prosesau biolegol • intermediate filament organization • cell differentiation • mRNA transport • mRNA export from nucleus • multicellular organism development • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • acrosome assembly • spermatogenesis • spermatid nucleus differentiation • membrane organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3267	n/a
Ensembl	ENSG00000173744	n/a
UniProt	P52594	n/a
RefSeq (mRNA)	NM_001135187 NM_001135188 NM_001135189 NM_004504	n/a
RefSeq (protein)	NP_001128659 NP_001128660 NP_001128661 NP_004495	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn AGFG1 yw AGFG1 a elwir hefyd yn ArfGAP with FG repeats 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q36.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AGFG1.

• HRB
• RAB
• RIP

Llyfryddiaeth

• "Human immunodeficiency virus rev-binding protein is essential for influenza a virus replication and promotes genome trafficking in late-stage infection. ". J Virol. 2011. PMID 21752912.
• "ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. ". BMC Med Genet. 2013. PMID 23984888.
• "Rabs, SNAREs and α-synuclein--membrane trafficking defects in synucleinopathies. ". Brain Res Rev. 2011. PMID 21439320.
• "Endosome-lysosome fusion. ". Biochem Soc Trans. 2010. PMID 21118098.
• "The cellular HIV-1 Rev cofactor hRIP is required for viral replication.". Proc Natl Acad Sci U S A. 2005. PMID 15749819.