ADRM1

ADRM1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2KQZ, 2KR0, 2L5V, 2MKZ, 4UEL, 4UEM, 4WLQ, 4WLR, 5IRS
Dynodwyr
Cyfenwau	ADRM1, ARM-1, ARM1, GP110, adhesion regulating molecule 1, PSMD16, ADRM1 26S proteasome ubiquitin receptor
Dynodwyr allanol	OMIM: 610650 HomoloGene: 10513 GeneCards: ADRM1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activator activity • protease binding • proteasome binding • GO:0001948, GO:0016582 protein binding • ubiquitin binding Cydrannau o'r gell • proteasome complex • Cellbilen • integral component of plasma membrane • bilen • cnewyllyn cell • nucleoplasm • cytoplasm • cytosol • proteasome regulatory particle, lid subcomplex Prosesau biolegol • transcription elongation from RNA polymerase II promoter • proteasome assembly • positive regulation of endopeptidase activity • ubiquitin-dependent protein catabolic process • protein deubiquitination Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11047	n/a
Ensembl	ENSG00000130706	n/a
UniProt	Q16186	n/a
RefSeq (mRNA)	NM_001281437 NM_001281438 NM_007002 NM_175573	n/a
RefSeq (protein)	NP_001268366 NP_001268367 NP_008933 NP_783163	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ADRM1 yw ADRM1 a elwir hefyd yn Adhesion regulating molecule 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20q13.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ADRM1.

• ARM1
• ARM-1
• GP110

Llyfryddiaeth

• "hRpn13, a newly identified component of the 19S particle, regulates proliferation, differentiation, and function in the human osteoblast-like cell line MG63. [corrected]. ". J Physiol Biochem. 2012. PMID 22057889.
• "[Silencing of Adrm1 by RNA interference suppresses proliferation of colorectal cancer cells]. ". Zhonghua Zhong Liu Za Zhi. 2009. PMID 20137344.
• "Knockdown of Adhesion-Regulating Molecule 1 Inhibits Proliferation in HL60 Cells. ". Acta Haematol. 2015. PMID 25896055.
• "ADRM1 gene amplification is a candidate driver for metastatic gastric cancers. ". Clin Exp Metastasis. 2014. PMID 24968865.
• "A possible connection between adhesion regulating molecule 1 overexpression and nuclear factor kappa B activity in hepatocarcinogenesis.". Oncol Rep. 2012. PMID 22576803.