ADGRE2

ADGRE2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BOX, 2BO2, 2BOU
Dynodwyr
Cyfenwau	ADGRE2, CD312, VBU, EMR2, adhesion G protein-coupled receptor E2, CD97
Dynodwyr allanol	OMIM: 606100 HomoloGene: 113735 GeneCards: ADGRE2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • chondroitin sulfate binding • transmembrane signaling receptor activity • signal transducer activity • G protein-coupled receptor activity Cydrannau o'r gell • ruffle membrane • Cellbilen • cell projection • bilen • leading edge membrane • integral component of membrane • intracellular anatomical structure • integral component of plasma membrane Prosesau biolegol • cell surface receptor signaling pathway • inflammatory response • cell migration • granulocyte chemotaxis • GO:0072468 signal transduction • G protein-coupled receptor signaling pathway • cell adhesion • regulation of mast cell degranulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	30817	n/a
Ensembl	ENSG00000127507	n/a
UniProt	Q9UHX3	n/a
RefSeq (mRNA)	NM_001271052 NM_013447 NM_152916 NM_152917 NM_152918 NM_152919 NM_152920 NM_152921	n/a
RefSeq (protein)	NP_001257981 NP_038475	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ADGRE2 yw ADGRE2 a elwir hefyd yn Adhesion G protein-coupled receptor E2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ADGRE2.

• VBU
• EMR2
• CD312

Llyfryddiaeth

• "Vibratory Urticaria Associated with a Missense Variant in ADGRE2. ". N Engl J Med. 2016. PMID 26841242.
• "Activation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains. ". Mol Cell Biol. 2012. PMID 22310662.
• "EMR2 receptor ligation modulates cytokine secretion profiles and cell survival of lipopolysaccharide-treated neutrophils. ". Chang Gung Med J. 2011. PMID 22035891.
• "Epidermal growth factor module-containing mucin-like receptor 2 is a newly identified adhesion G protein-coupled receptor associated with poor overall survival and an invasive phenotype in glioblastoma. ". J Neurooncol. 2011. PMID 21503828.
• "Leukocyte adhesion-GPCR EMR2 is aberrantly expressed in human breast carcinomas and is associated with patient survival.". Oncol Rep. 2011. PMID 21174063.