ACTB

ACTB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3BYH, 3D2U, 3J82, 3LUE
Dynodwyr
Cyfenwau	ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin, beta, actin beta
Dynodwyr allanol	OMIM: 102630 HomoloGene: 110648 GeneCards: ACTB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • nucleotide binding • nitric-oxide synthase binding • Tat protein binding • structural constituent of cytoskeleton • GO:0001948, GO:0016582 protein binding • kinesin binding • identical protein binding • nucleosomal DNA binding • ATP binding Cydrannau o'r gell • cytoplasm • blood microparticle • bilen • focal adhesion • NuA4 histone acetyltransferase complex • Cellbilen • nucleoplasm • cytoplasmic ribonucleoprotein granule • extracellular exosome • Cytosgerbwd • dense body • cortical cytoskeleton • cytosol • myelin sheath • extracellular space Prosesau biolegol • epigenetic maintenance of chromatin in transcription-competent conformation • substantia nigra development • Fc-gamma receptor signaling pathway involved in phagocytosis • ephrin receptor signaling pathway • retina homeostasis • vascular endothelial growth factor receptor signaling pathway • platelet aggregation • cell junction assembly • cytoskeleton organization • protein deubiquitination • membrane organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	60	n/a
Ensembl	ENSG00000075624	n/a
UniProt	P60709	n/a
RefSeq (mRNA)	NM_001101	n/a
RefSeq (protein)	NP_001092	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ACTB yw ACTB a elwir hefyd yn Actin, cytoplasmic 1 ac Actin beta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ACTB.

• BRWS1
• PS1TP5BP1

Llyfryddiaeth

• "ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder. ". Am J Hum Genet. 2017. PMID 29220674.
• "ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. ". J Cell Biol. 2017. PMID 29150539.
• "7p22.1 microduplication syndrome: Refinement of the critical region. ". Eur J Med Genet. 2017. PMID 27866048.
• "7p22.1 microdeletions involving ACTB associated with developmental delay, short stature, and microcephaly. ". Eur J Med Genet. 2016. PMID 27633570.
• "Baraitser-Winter cerebrofrontofacial syndrome.". Clin Genet. 2017. PMID 27625340.