ACP5

ACP5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BQ8, 1WAR
Dynodwyr
Cyfenwau	ACP5, HPAP, SPENCDI, TRAP, TRACP5a, TRACP5b, TrATPase, acid phosphatase 5, tartrate resistant, TRAcP
Dynodwyr allanol	OMIM: 171640 HomoloGene: 115578 GeneCards: ACP5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ferric iron binding • acid phosphatase activity • metal ion binding • ferrous iron binding • hydrolase activity Cydrannau o'r gell • integral component of membrane • cytosol • lysosome Prosesau biolegol • riboflavin metabolic process • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • response to lipopolysaccharide • negative regulation of interleukin-1 beta production • negative regulation of interleukin-12 production • negative regulation of tumor necrosis factor production • negative regulation of superoxide anion generation • response to cytokine • negative regulation of nitric oxide biosynthetic process • bone resorption • negative regulation of inflammatory response • GO:0051637 defense response to Gram-positive bacterium • bone morphogenesis • ossification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	54	n/a
Ensembl	ENSG00000102575	n/a
UniProt	P13686	n/a
RefSeq (mRNA)	NM_001111034 NM_001111035 NM_001111036 NM_001611 NM_001322023	n/a
RefSeq (protein)	NP_001104504 NP_001104505 NP_001104506 NP_001308952 NP_001602	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ACP5 yw ACP5 a elwir hefyd yn Tartrate-resistant acid phosphatase type 5 ac Acid phosphatase 5, tartrate resistant (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ACP5.

• HPAP
• TRAP
• TRACP5a
• TRACP5b
• TrATPase

Llyfryddiaeth

• "Childhood-onset autoimmune cytopenia as the presenting feature of biallelic ACP5 mutations. ". Pediatr Blood Cancer. 2017. PMID 27718324.
• "Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus. ". Arthritis Rheumatol. 2017. PMID 27390188.
• "[TARTRAT-RESISTANT ACID PHOSPHATASE AS BONE'S RESORBTION MARKER IN PATIENTS WITH BONE METASTASES]. ". Lik Sprava. 2015. PMID 27089726.
• "Spondyloenchondrodysplasia Due to Mutations in ACP5: A Comprehensive Survey. ". J Clin Immunol. 2016. PMID 26951490.
• "Three cases of spondyloenchondrodysplasia (SPENCD) with systemic lupus erythematosus: a case series and review of the literature.". Lupus. 2016. PMID 26854080.