ACE2

ACE2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3SCL, 1R42, 1R4L, 2AJF, 3D0G, 3D0H, 3D0I, 3KBH, 3SCI, 3SCJ, 3SCK
Dynodwyr
Cyfenwau	ACE2, ACEH, angiotensin I converting enzyme 2, ACE 2
Dynodwyr allanol	OMIM: 300335 HomoloGene: 41448 GeneCards: ACE2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidyl-dipeptidase activity • virus receptor activity • zinc ion binding • endopeptidase activity • metal ion binding • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • carboxypeptidase activity • hydrolase activity • metallopeptidase activity • metallocarboxypeptidase activity • exopeptidase activity Cydrannau o'r gell • cytoplasm • integral component of membrane • bilen • Cellbilen • extracellular region • cell surface • membrane raft • extracellular exosome • extracellular space • brush border membrane Prosesau biolegol • regulation of cardiac conduction • angiotensin-mediated drinking behavior • proteolysis • GO:0032657 regulation of cytokine production • positive regulation of reactive oxygen species metabolic process • regulation of vasoconstriction • regulation of cell population proliferation • positive regulation of cardiac muscle contraction • regulation of inflammatory response • positive regulation of gap junction assembly • viral entry into host cell • GO:0022415 viral process • regulation of systemic arterial blood pressure by renin-angiotensin • tryptophan transport • blood vessel diameter maintenance • angiotensin maturation • receptor-mediated virion attachment to host cell • positive regulation of amino acid transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	59272	n/a
Ensembl	ENSG00000130234	n/a
UniProt	Q9BYF1	n/a
RefSeq (mRNA)	NM_021804 NM_001371415	n/a
RefSeq (protein)	NP_068576 NP_001358344	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ACE2 yw ACE2 a elwir hefyd yn Angiotensin I converting enzyme 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xp22.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ACE2.

• ACEH

Llyfryddiaeth

• "Overexpression of Angiotensin-Converting Enzyme 2 Ameliorates Amyloid β-Induced Inflammatory Response in Human Primary Retinal Pigment Epithelium. ". Invest Ophthalmol Vis Sci. 2017. PMID 28605813.
• "Association between circulating angiotensin-converting enzyme 2 and cardiac remodeling in hypertensive patients. ". Peptides. 2017. PMID 28223093.
• "Circulating ACE2 activity correlates with cardiovascular disease development. ". J Renin Angiotensin Aldosterone Syst. 2016. PMID 27965422.
• "ACE2 and the Homolog Collectrin in the Modulation of Nitric Oxide and Oxidative Stress in Blood Pressure Homeostasis and Vascular Injury. ". Antioxid Redox Signal. 2017. PMID 27889958.
• "Angiotensin-converting enzyme 2 is reduced in Alzheimer's disease in association with increasing amyloid-β and tau pathology.". Alzheimers Res Ther. 2016. PMID 27884212.