ACAD8

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ACAD8
Protein ACAD8 PDB 1rx0.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauACAD8, ACAD-8, ARC42, acyl-CoA dehydrogenase family member 8
Dynodwyr allanolMGI: 1914198 HomoloGene: 8662 GeneCards: ACAD8
Patrwm RNA pattern
PBB GE ACAD8 221669 s at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014384

NM_025862

RefSeq (protein)

NP_055199

NP_080138

Lleoliad (UCSC)n/aChr : 26.97 – 27 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn ACAD8 yw ACAD8 a elwir hefyd yn Acyl-CoA dehydrogenase family member 8 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q25.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ACAD8.

  • ARC42
  • ACAD-8

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans. ". Mol Genet Metab. 2002. PMID 12359132.
  • "Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism. ". Am J Hum Genet. 2000. PMID 11013134.
  • "A novel ACAD8 mutation in asymptomatic patients with isobutyryl-CoA dehydrogenase deficiency and a review of the ACAD8 mutation spectrum. ". Clin Genet. 2015. PMID 24635911.
  • "Structures of isobutyryl-CoA dehydrogenase and enzyme-product complex: comparison with isovaleryl- and short-chain acyl-CoA dehydrogenases. ". J Biol Chem. 2004. PMID 14752098.
  • "Isolation and characterisation of a cDNA encoding the precursor for a novel member of the acyl-CoA dehydrogenase gene family.". Biochim Biophys Acta. 1999. PMID 10524212.

Cyfeiriadau[golygu | golygu cod y dudalen]