ABCC1

Oddi ar Wicipedia
Jump to navigation Jump to search
ABCC1
Protein ABCC1 PDB 2cbz.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauABCC1, ABC29, ABCC, GS-X, MRP, MRP1, ATP binding cassette subfamily C member 1
Dynodwyr allanolMGI: 102676 HomoloGene: 133779 GeneCards: ABCC1
Patrwm RNA pattern
PBB GE ABCC1 202805 s at fs.png

PBB GE ABCC1 202804 at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_008576

RefSeq (protein)

NP_004987

NP_032602

Lleoliad (UCSC)n/aChr : 14.36 – 14.48 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn ABCC1 yw ABCC1 a elwir hefyd yn ATP binding cassette subfamily C member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p13.11.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ABCC1.

  • MRP
  • ABCC
  • GS-X
  • MRP1
  • ABC29

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Hedgehog signaling pathway affects the sensitivity of hepatoma cells to drug therapy through the ABCC1 transporter. ". Lab Invest. 2017. PMID 28414325.
  • "Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation. ". Biochem Biophys Res Commun. 2017. PMID 27908733.
  • "ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy. ". Sci Transl Med. 2016. PMID 27535620.
  • "Arsenic Triglutathione [As(GS)3] Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) Is Selectively Modified by Phosphorylation of Tyr920/Ser921 and Glycosylation of Asn19/Asn23. ". Mol Pharmacol. 2016. PMID 27297967.
  • "Chaetominine reduces MRP1-mediated drug resistance via inhibiting PI3K/Akt/Nrf2 signaling pathway in K562/Adr human leukemia cells.". Biochem Biophys Res Commun. 2016. PMID 27038543.

Cyfeiriadau[golygu | golygu cod y dudalen]