A1CF

A1CF
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CPD
Dynodwyr
Cyfenwau	A1CF, ACF, ACF64, ACF65, APOBEC1CF, ASP, APOBEC1 complementation factor
Dynodwyr allanol	OMIM: 618199 HomoloGene: 16363 GeneCards: A1CF
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleic acid binding • double-stranded RNA binding • GO:0001948, GO:0016582 protein binding • single-stranded RNA binding • RNA binding • mRNA binding Cydrannau o'r gell • cytoplasm • apolipoprotein B mRNA editing enzyme complex • Reticwlwm endoplasmig • cnewyllyn cell • nucleoplasm Prosesau biolegol • mRNA processing • protein stabilization • cytidine to uridine editing • mRNA modification • mRNA localization resulting in posttranscriptional regulation of gene expression Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	29974	n/a
Ensembl	ENSG00000148584	n/a
UniProt	Q9NQ94	n/a
RefSeq (mRNA)	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933 NM_001370130 NM_001370131	n/a
RefSeq (protein)	NP_001185747 NP_001185748 NP_001185749 NP_055391 NP_620310 NP_620311 NP_001357059 NP_001357060	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn A1CF yw A1CF a elwir hefyd yn APOBEC1 complementation factor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q11.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn A1CF.

• ACF
• ASP
• ACF64
• ACF65
• APOBEC1CF

Llyfryddiaeth

• "Induction of cytidine to uridine editing on cytoplasmic apolipoprotein B mRNA by overexpressing APOBEC-1. ". J Biol Chem. 2000. PMID 10833526.
• "EIYMNVPV Motif is Essential for A1CF Nucleus Localization and A1CF (-8aa) Promotes Proliferation of MDA-MB-231 Cells via Up-Regulation of IL-6. ". Int J Mol Sci. 2016. PMID 27231908.
• "Isolation, characterization and developmental regulation of the human apobec-1 complementation factor (ACF) gene. ". Biochim Biophys Acta. 2001. PMID 11718896.
• "Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation of C to U RNA-editing activity. ". J Biol Chem. 2001. PMID 11571303.
• "RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA.". Biochim Biophys Acta. 2000. PMID 11072063.