VTN

VTN
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1OC0, 1S4G, 1SSU, 2JQ8, 3BT1, 3BT2, 4K24
Dynodwyr
Cyfenwau	VTN, V75, VN, VNT, vitronectin
Dynodwyr allanol	OMIM: 193190 HomoloGene: 532 GeneCards: VTN
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • scavenger receptor activity • heparin binding • extracellular matrix binding • polysaccharide binding • integrin binding • identical protein binding • collagen binding • extracellular matrix structural constituent Cydrannau o'r gell • alphav-beta3 integrin-vitronectin complex • extracellular exosome • blood microparticle • Golgi lumen • basement membrane • rough endoplasmic reticulum lumen • cytoplasm • GO:0005578 extracellular matrix • extracellular space • Reticwlwm endoplasmig • intracellular membrane-bounded organelle • extracellular region • collagen-containing extracellular matrix Prosesau biolegol • receptor-mediated endocytosis • positive regulation of protein binding • cell adhesion • positive regulation of cell-substrate adhesion • extracellular matrix organization • smooth muscle cell-matrix adhesion • regulation of complement activation • positive regulation of smooth muscle cell migration • negative regulation of endopeptidase activity • positive regulation of peptidyl-tyrosine phosphorylation • positive regulation of vascular endothelial growth factor receptor signaling pathway • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • endodermal cell differentiation • positive regulation of wound healing • positive regulation of receptor-mediated endocytosis • negative regulation of blood coagulation • oligodendrocyte differentiation • cell adhesion mediated by integrin • cell-matrix adhesion • protein polymerization • liver regeneration • cell population proliferation • cell migration • vesicle-mediated transport • endocytosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7448	n/a
Ensembl	ENSG00000109072	n/a
UniProt	P04004	n/a
RefSeq (mRNA)	NM_000638	n/a
RefSeq (protein)	NP_000629	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn VTN yw VTN a elwir hefyd yn Vitronectin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn VTN.

• VN
• V75
• VNT

Llyfryddiaeth

• "The Rickettsia conoriiAdr1 Interacts with the C-Terminus of Human Vitronectin in a Salt-Sensitive Manner. ". Front Cell Infect Microbiol. 2017. PMID 28299286.
• "Diagnostic and prognostic value of serum vitronectin levels in human glioma. ". J Neurol Sci. 2016. PMID 27871448.
• "Diagnostic and prognostic roles of serum vitronectin in hepatitis B-related hepatocellular carcinoma. ". Cancer Biomark. 2016. PMID 27802203.
• "Urokinase links plasminogen activation and cell adhesion by cleavage of the RGD motif in vitronectin. ". EMBO Rep. 2016. PMID 27189837.
• "Vitronectin significantly influences prognosis in osteosarcoma.". Int J Clin Exp Pathol. 2015. PMID 26617861.