TGFA

TGFA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1GK5, 1MOX, 1YUF, 1YUG, 2TGF, 3E50, 3TGF, 4TGF
Dynodwyr
Cyfenwau	TGFA, TFGA, transforming growth factor alpha, Transforming growth factor - α
Dynodwyr allanol	OMIM: 190170 HomoloGene: 2431 GeneCards: TGFA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • epidermal growth factor receptor binding • GO:0001948, GO:0016582 protein binding • growth factor activity Cydrannau o'r gell • integral component of membrane • endoplasmic reticulum membrane • bilen • Cellbilen • integral component of plasma membrane • extracellular region • cell surface • basolateral plasma membrane • perinuclear region of cytoplasm • ER to Golgi transport vesicle membrane • endoplasmic reticulum-Golgi intermediate compartment membrane • GO:0016023 cytoplasmic vesicle • Golgi membrane • extracellular space • clathrin-coated vesicle membrane Prosesau biolegol • positive regulation of epidermal growth factor-activated receptor activity • positive regulation of epithelial cell proliferation • endoplasmic reticulum to Golgi vesicle-mediated transport • COPII vesicle coating • cell population proliferation • positive regulation of mitotic nuclear division • positive regulation of cell division • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • epidermal growth factor receptor signaling pathway • positive regulation of cell population proliferation • MAPK cascade • GO:0072468 signal transduction • negative regulation of epidermal growth factor receptor signaling pathway • positive regulation of protein kinase B signaling • membrane organization • GO:0007243 intracellular signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7039	n/a
Ensembl	ENSG00000163235	n/a
UniProt	P01135	n/a
RefSeq (mRNA)	NM_001099691 NM_001308158 NM_001308159 NM_003236	n/a
RefSeq (protein)	NP_001093161 NP_001295087 NP_001295088 NP_003227	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TGFA yw TGFA a elwir hefyd yn Transforming growth factor alpha (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TGFA.

• TFGA

Llyfryddiaeth

• "Tagging staphylococcal enterotoxin B (SEB) with TGFaL3 for breast cancer therapy. ". Tumour Biol. 2016. PMID 26561468.
• "Possible implications of TGF-alpha in oesophageal dysmotility in systemic sclerosis. ". Clin Exp Rheumatol. 2014. PMID 25083591.
• "Association between polymorphism of TGFA Taq I and cleft lip and/or palate: a meta-analysis. ". BMC Oral Health. 2014. PMID 25015300.
• "A novel SNP associated with nighttime pulse pressure in young-onset hypertension patients could be a genetic prognostic factor for cardiovascular events in a general cohort in Taiwan. ". PLoS One. 2014. PMID 24892410.
• "Contribution of transforming growth factor α polymorphisms to nonsyndromic orofacial clefts: a HuGE review and meta-analysis.". Am J Epidemiol. 2014. PMID 24243742.