SVIL

SVIL
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2K6M, 2K6N
Dynodwyr
Cyfenwau	SVIL, supervillin, MFM10
Dynodwyr allanol	OMIM: 604126 HomoloGene: 25090 GeneCards: SVIL
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin filament binding • actin binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • microtubule minus-end • podosome • cell junction • Cellbilen • cell projection • midbody • cleavage furrow • costamere • Cytosgerbwd • bilen • cnewyllyn cell • focal adhesion • actin cytoskeleton • cytosol Prosesau biolegol • positive regulation of cytokinesis • skeletal muscle tissue development • cytoskeleton organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6840	n/a
Ensembl	ENSG00000197321	n/a
UniProt	O95425	n/a
RefSeq (mRNA)	NM_003174 NM_021738 NM_001323599 NM_001323600	n/a
RefSeq (protein)	NP_001310528 NP_001310529 NP_003165 NP_068506	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SVIL yw SVIL a elwir hefyd yn Supervillin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10p11.23.

Llyfryddiaeth

• "Villin-type headpiece domains show a wide range of F-actin-binding affinities. ". Cell Motil Cytoskeleton. 2002. PMID 11977079.
• "Domain analysis of supervillin, an F-actin bundling plasma membrane protein with functional nuclear localization signals. ". J Cell Sci. 1999. PMID 10362542.
• "The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility. ". Traffic. 2010. PMID 20331534.
• "How to arm a supervillin: designing F-actin binding activity into supervillin headpiece. ". J Mol Biol. 2009. PMID 19683541.
• "Supervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency.". Mol Biol Cell. 2009. PMID 19109420.