SP1

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SP1
Protein SP1 PDB 1sp1.png
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauSP1, entrez:6667, Sp1 transcription factor
Dynodwyr allanolOMIM: 189906 HomoloGene: 8276 GeneCards: SP1
Patrwm RNA pattern
PBB GE SP1 214732 at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001251825
NM_003109
NM_138473

n/a

RefSeq (protein)

NP_001238754
NP_003100
NP_612482

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SP1 yw SP1 a elwir hefyd yn Sp1 transcription factor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q13.13.[2]

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Specificity protein 1: Its role in colorectal cancer progression and metastasis. ". Crit Rev Oncol Hematol. 2017. PMID 28427500.
  • "Glucose-derived AGEs promote migration and invasion of colorectal cancer by up-regulating Sp1 expression. ". Biochim Biophys Acta. 2017. PMID 28237576.
  • "Effects of Cu(II) and cisplatin on the stability of Specific protein 1 (Sp1)-DNA binding: Insights into the regulation of copper homeostasis and platinum drug transport. ". J Inorg Biochem. 2016. PMID 27172866.
  • "Starvation after Cobalt-60 γ-Ray Radiation Enhances Metastasis in U251 Glioma Cells by Regulating the Transcription Factor SP1. ". Int J Mol Sci. 2016. PMID 27058528.
  • "MiR-24 enhances radiosensitivity in nasopharyngeal carcinoma by targeting SP1.". Cancer Med. 2016. PMID 26922862.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. "Human PubMed Reference:".
  2. SP1 - Cronfa NCBI