SNF8 Dynodwyr Cyfenwau SNF8 Dynodwyr allanol OMIM: 610904 HomoloGene: 5239 GeneCards: SNF8 Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • protein N-terminus binding • transcription factor binding • protein C-terminus binding • channel regulator activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • recycling endosome • cytosol • endosome • bilen • late endosome membrane • transcription regulator complex • Cellbilen • nucleoplasm • perinuclear region of cytoplasm • endosome membrane • extracellular exosome • cnewyllyn cell • ESCRT II complex Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • GO:1903364 positive regulation of protein catabolic process • multivesicular body sorting pathway • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • multivesicular body assembly • regulation of multivesicular body size involved in endosome transport • transcription, DNA-templated • endosomal transport • regulation of protein complex stability • GO:1901313 positive regulation of gene expression • early endosome to late endosome transport • endocytic recycling • GO:1903362 regulation of protein catabolic process • protein transport • regulation of MAP kinase activity • positive regulation of exosomal secretion • protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway • macroautophagy • regulation of molecular function • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau Species Bod dynol Llygoden Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Lleoliad (UCSC) n/a n/a PubMed search[1] n/a Wicidata
Protein sy'n cael ei godio yn y corff dynol gan y genyn SNF8 yw SNF8 a elwir hefyd yn SNF8, ESCRT-II complex subunit (Saesneg). Segment o DNA yw'r genyn , sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q21.32.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SNF8.
"Identification of CAD candidate genes in GWAS loci and their expression in vascular cells. ". J Lipid Res . 2013. PMID 23667179 . "RILP interacts with the VPS22 component of the ESCRT-II complex. ". Biochem Biophys Res Commun . 2006. PMID 16857164 . "Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking. ". Exp Cell Res . 2008. PMID 18031739 . "Pivotal role for the ESCRT-II complex subunit EAP30/SNF8 in IRF3-dependent innate antiviral defense. ". PLoS Pathog . 2017. PMID 29084253 . "Inhibition of ESCRT-II-CHMP6 interactions impedes cytokinetic abscission and leads to cell death. ". Mol Biol Cell . 2014. PMID 25232011 . 
