SLC3A2

SLC3A2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DH2, 2DH3
Dynodwyr
Cyfenwau	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE, solute carrier family 3 member 2
Dynodwyr allanol	OMIM: 158070 HomoloGene: 1795 GeneCards: SLC3A2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium:sodium antiporter activity • neutral amino acid transmembrane transporter activity • catalytic activity • GO:0001948, GO:0016582 protein binding • double-stranded RNA binding • RNA binding • cadherin binding Cydrannau o'r gell • integral component of membrane • bilen • melanosome • Cellbilen • cell surface • apical plasma membrane • extracellular exosome • cnewyllyn cell • cytosol Prosesau biolegol • response to exogenous dsRNA • cell growth • amino acid transport • leukocyte migration • calcium ion transport • tryptophan transport • sodium ion transmembrane transport • L-alpha-amino acid transmembrane transport • GO:0015915 transport • carbohydrate metabolic process • L-leucine import across plasma membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6520	n/a
Ensembl	ENSG00000168003	n/a
UniProt	P08195	n/a
RefSeq (mRNA)	NM_001012661 NM_001012662 NM_001012663 NM_001012664 NM_001013251 NM_002394	n/a
RefSeq (protein)	NP_001012680 NP_001012682 NP_001013269 NP_002385	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SLC3A2 yw SLC3A2 a elwir hefyd yn 4F2 cell-surface antigen heavy chain a Solute carrier family 3 member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q12.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SLC3A2.

• 4F2
• CD98
• MDU1
• 4F2HC
• 4T2HC
• NACAE
• CD98HC

Llyfryddiaeth

• "Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc. ". Proc Natl Acad Sci U S A. 2014. PMID 24516142.
• "Identification of anti-CD98 antibody mimotopes for inducing antibodies with antitumor activity by mimotope immunization. ". Cancer Sci. 2014. PMID 24484217.
• "Prognostic Significance of the Expression of CD98 (4F2hc) in Gastric Cancer. ". Anticancer Res. 2017. PMID 28179310.
• "Brucella Intracellular Life Relies on the Transmembrane Protein CD98 Heavy Chain. ". J Infect Dis. 2015. PMID 25505297.
• "Genetic variations in SLC3A2/CD98 gene as prognosis predictors in non-small cell lung cancer.". Mol Carcinog. 2015. PMID 24782339.