PRPSAP1

PRPSAP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2C4K
Dynodwyr
Cyfenwau	PRPSAP1, PAP39, phosphoribosyl pyrophosphate synthetase-associated protein 1, phosphoribosyl pyrophosphate synthetase associated protein 1
Dynodwyr allanol	OMIM: 601249 HomoloGene: 55687 GeneCards: PRPSAP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0048551 enzyme inhibitor activity • ribose phosphate diphosphokinase activity • magnesium ion binding • GO:0001948, GO:0016582 protein binding • identical protein binding • GO:0010576 enzyme regulator activity Cydrannau o'r gell • ribose phosphate diphosphokinase complex • cytoplasm Prosesau biolegol • nucleotide biosynthetic process • nucleobase-containing compound metabolic process • GO:0048553 negative regulation of catalytic activity • 5-phosphoribose 1-diphosphate biosynthetic process • purine nucleotide biosynthetic process • GO:0048552 regulation of catalytic activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5635	n/a
Ensembl	ENSG00000161542	n/a
UniProt	Q14558	n/a
RefSeq (mRNA)	NM_002766 NM_001330503 NM_001366236	n/a
RefSeq (protein)	NP_001317432 NP_002757 NP_001353165	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRPSAP1 yw PRPSAP1 a elwir hefyd yn Phosphoribosyl pyrophosphate synthetase associated protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRPSAP1.

• PAP39

Llyfryddiaeth

• "Mammalian phosphoribosyl-pyrophosphate synthetase. ". Adv Enzyme Regul. 1995. PMID 7572345.
• "Partial reconstitution of mammalian phosphoribosylpyrophosphate synthetase in Escherichia coli cells. Coexpression of catalytic subunits with the 39-kDa associated protein leads to formation of soluble multimeric complexes of various compositions. ". Biochim Biophys Acta. 1997. PMID 9366267.
• "The human phosphoribosylpyrophosphate synthetase-associated protein 39 gene (PRPSAP1) is located in the chromosome region 17q24-q25. ". Genomics. 1996. PMID 8660991.
• "Cloning and sequencing of human complementary DNA for the phosphoribosylpyrophosphate synthetase-associated protein 39. ". Biochim Biophys Acta. 1996. PMID 8611620.
• "A novel 39-kDa phosphoribosylpyrophosphate synthetase-associated protein of rat liver. Cloning, high sequence similarity to the catalytic subunits, and a negative regulatory role.". J Biol Chem. 1994. PMID 8132556.