PLG

PLG
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1B2I, 1BML, 1BUI, 1CEA, 1CEB, 1DDJ, 1HPJ, 1HPK, 1I5K, 1KI0, 1KRN, 1L4D, 1L4Z, 1PK4, 1PKR, 1PMK, 1QRZ, 1RJX, 2DOH, 2DOI, 2KNF, 2L0S, 2PK4, 3UIR, 4A5T, 4CIK, 4DCB, 4DUR, 4DUU, 5HPG
Dynodwyr
Cyfenwau	PLG, plasminogen, plasmin, HAE4
Dynodwyr allanol	OMIM: 173350 HomoloGene: 55452 GeneCards: PLG
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • apolipoprotein binding • protein domain specific binding • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • serine-type peptidase activity • signaling receptor binding • hydrolase activity • serine-type endopeptidase activity • chaperone binding • proteasome core complex binding • protein antigen binding • endopeptidase activity • enzyme binding • kinase binding Cydrannau o'r gell • blood microparticle • extracellular region • cell surface • extrinsic component of external side of plasma membrane • extracellular exosome • platelet alpha granule lumen • extracellular space • Cellbilen • extrinsic component of plasma membrane • intracellular membrane-bounded organelle • collagen-containing extracellular matrix Prosesau biolegol • hemostasis • negative regulation of cell-substrate adhesion • negative regulation of fibrinolysis • negative regulation of cell-cell adhesion mediated by cadherin • platelet degranulation • extracellular matrix disassembly • positive regulation of fibrinolysis • tissue remodeling • negative regulation of cell population proliferation • blood coagulation • proteolysis • fibrinolysis • positive regulation of blood vessel endothelial cell migration • tissue regeneration • myoblast differentiation • muscle cell cellular homeostasis • proteolysis involved in cellular protein catabolic process • trophoblast giant cell differentiation • labyrinthine layer blood vessel development • mononuclear cell migration Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5340	n/a
Ensembl	ENSG00000122194	n/a
UniProt	P00747	n/a
RefSeq (mRNA)	NM_001168338 NM_000301	n/a
RefSeq (protein)	NP_000292 NP_001161810	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PLG yw PLG a elwir hefyd yn Plasminogen (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q26.

Llyfryddiaeth

• "Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients. ". G3 (Bethesda). 2016. PMID 27194806.
• "No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome. ". Int J Hematol. 2016. PMID 27194432.
• "Conformationally organized lysine isosteres in Streptococcus pyogenesM protein mediate direct high-affinity binding to human plasminogen. ". J Biol Chem. 2017. PMID 28724633.
• "Plasmin(ogen) serves as a favorable biomarker for prediction of survival in advanced high-grade serous ovarian cancer. ". Biol Chem. 2017. PMID 27935848.
• "Penicillin binding protein 3 of Staphylococcus aureus NCTC 8325-4 binds and activates human plasminogen.". BMC Res Notes. 2016. PMID 27488131.