PLEKHB2

PLEKHB2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3AJ4, 3VIA
Dynodwyr
Cyfenwau	PLEKHB2, EVT2, pleckstrin homology domain containing B2
Dynodwyr allanol	OMIM: 618452 HomoloGene: 9938 GeneCards: PLEKHB2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • phosphatidylinositol-3,4,5-trisphosphate binding Cydrannau o'r gell • bilen • recycling endosome membrane • endosome • integral component of membrane Prosesau biolegol • regulation of cell differentiation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	55041	n/a
Ensembl	ENSG00000115762	n/a
UniProt	Q96CS7	n/a
RefSeq (mRNA)	NM_001031706 NM_001100623 NM_001267062 NM_001267063 NM_001267064 NM_001267065 NM_001267066 NM_001267067 NM_001267068 NM_001309448 NM_001309450 NM_001309451 NM_001309452 NM_017958	n/a
RefSeq (protein)	NP_001094093 NP_001253991 NP_001253992 NP_001253993 NP_001253994 NP_001253995 NP_001253996 NP_001253997 NP_001296377 NP_001296379 NP_001296380 NP_001296381 NP_060428 NP_001094093.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PLEKHB2 yw PLEKHB2 a elwir hefyd yn Pleckstrin homology domain containing, family B (Evectins) member 2, isoform CRA_b a Pleckstrin homology domain containing B2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PLEKHB2.

• EVT2

Llyfryddiaeth

• "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. ". Biochem J. 2000. PMID 11001876.
• "The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines. ". EMBO J. 2014. PMID 25260751.
• "Structural basis of the strict phospholipid binding specificity of the pleckstrin homology domain of human evectin-2. ". Acta Crystallogr D Biol Crystallogr. 2012. PMID 22281740.
• "Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes. ". Proc Natl Acad Sci U S A. 2011. PMID 21911378.
• "Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes.". Proc Natl Acad Sci U S A. 1999. PMID 10200314.