KIF22

KIF22
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2EDU, 3BFN
Dynodwyr
Cyfenwau	KIF22, A-328A3.2, KID, KNSL4, OBP, OBP-1, OBP-2, SEMDJL2, kinesin family member 22
Dynodwyr allanol	OMIM: 603213 HomoloGene: 32011 GeneCards: KIF22
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • nucleotide binding • microtubule binding • ATPase activity • GO:0001948, GO:0016582 protein binding • ATP binding • microtubule motor activity Cydrannau o'r gell • kinesin complex • spindle • chromatin • mitotic spindle • microtubule • Cytosgerbwd • kinetochore • cnewyllyn cell • cytoplasm • cytosol • nuclear speck Prosesau biolegol • metaphase plate congression • antigen processing and presentation of exogenous peptide antigen via MHC class II • sister chromatid cohesion • microtubule-based movement • mitotic metaphase plate congression • GO:0100026 DNA repair • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • GO:0007067 Mitosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3835	n/a
Ensembl	ENSG00000079616	n/a
UniProt	Q14807	n/a
RefSeq (mRNA)	NM_001256269 NM_001256270 NM_007317	n/a
RefSeq (protein)	NP_001243198 NP_001243199 NP_015556	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KIF22 yw KIF22 a elwir hefyd yn Kinesin family member 22 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KIF22.

• KID
• OBP
• KNSL4
• OBP-1
• OBP-2
• SEMDJL2
• A-328A3.2

Llyfryddiaeth

• "Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity. ". Am J Hum Genet. 2011. PMID 22152678.
• "Whole-exome sequencing identifies mutations of KIF22 in spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type. ". Am J Hum Genet. 2011. PMID 22152677.
• "Human Kid is degraded by the APC/C(Cdh1) but not by the APC/C(Cdc20). ". Cell Cycle. 2007. PMID 17726374.
• "The chromokinesin Kid is required for maintenance of proper metaphase spindle size. ". Mol Biol Cell. 2005. PMID 16176979.
• "The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles.". J Cell Biol. 2001. PMID 11564754.