IL5

IL5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3VA2, 1HUL, 3QT2
Dynodwyr
Cyfenwau	IL5, EDF, IL-5, TRF, interleukin 5
Dynodwyr allanol	OMIM: 147850 HomoloGene: 679 GeneCards: IL5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • interleukin-5 receptor binding • GO:0001948, GO:0016582 protein binding • growth factor activity • protein tyrosine kinase activity • cytokine activity Cydrannau o'r gell • extracellular region • intracellular anatomical structure • extracellular space Prosesau biolegol • positive regulation of DNA-binding transcription factor activity • positive regulation of podosome assembly • MAPK cascade • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of cell population proliferation • positive regulation of eosinophil differentiation • positive regulation of peptidyl-tyrosine phosphorylation • inflammatory response • positive regulation of receptor signaling pathway via JAK-STAT • peptidyl-tyrosine phosphorylation • positive regulation of B cell proliferation • regulation of signaling receptor activity • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3567	n/a
Ensembl	ENSG00000113525	n/a
UniProt	P05113	n/a
RefSeq (mRNA)	NM_000879	n/a
RefSeq (protein)	NP_000870	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL5 yw IL5 a elwir hefyd yn Interleukin 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL5.

• EDF
• TRF
• IL-5

Llyfryddiaeth

• "Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease. ". Cytokine. 2016. PMID 26821299.
• "IL-5, IL-8 and MMP -9 levels in exhaled breath condensate of atopic and nonatopic asthmatic children. ". Respir Med. 2015. PMID 25937050.
• "IL-5 production by resident mucosal allergen-specific T cells in an explant model of allergic rhinitis. ". Clin Exp Allergy. 2015. PMID 25817862.
• "Plasma IL-5 concentration and subclinical carotid atherosclerosis. ". Atherosclerosis. 2015. PMID 25587992.
• "Cholesterol selectively regulates IL-5 induced mitogen activated protein kinase signaling in human eosinophils.". PLoS One. 2014. PMID 25121926.