HOMER2

HOMER2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1I7A
Dynodwyr
Cyfenwau	HOMER2, ACPD, CPD, HOMER-2, VESL-2, DFNA68, homer scaffolding protein 2, homer scaffold protein 2
Dynodwyr allanol	OMIM: 604799 HomoloGene: 3560 GeneCards: HOMER2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • protein homodimerization activity • protein domain specific binding • synaptic receptor adaptor activity • actin binding • G protein-coupled glutamate receptor binding • glutamate receptor binding • protein heterodimerization activity Cydrannau o'r gell • cytoplasm • neuronal cell body • postsynaptic membrane • dendrite • synapse • GO:0097483, GO:0097481 postsynaptic density • bilen • apical part of cell • stereocilium tip • cell projection • stereocilium • Cellbilen • cell junction • cytosol • glutamatergic synapse • neuron projection Prosesau biolegol • G protein-coupled glutamate receptor signaling pathway • chemical homeostasis within a tissue • behavioral response to cocaine • regulation of G protein-coupled receptor signaling pathway • sensory perception of sound • calcium-mediated signaling using intracellular calcium source • negative regulation of interleukin-2 production • negative regulation of calcineurin-NFAT signaling cascade • regulation of store-operated calcium entry • positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9455	n/a
Ensembl	ENSG00000103942	n/a
UniProt	Q9NSB8	n/a
RefSeq (mRNA)	NM_004839 NM_199330 NM_199331 NM_199332	n/a
RefSeq (protein)	NP_004830 NP_955362	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HOMER2 yw HOMER2 a elwir hefyd yn Homer scaffolding protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q25.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HOMER2.

• CPD
• ACPD
• DFNA68
• VESL-2
• HOMER-2

Llyfryddiaeth

• "Potential role of Homer-2a on cutaneous vascular anomaly. ". J Korean Med Sci. 2002. PMID 12378015.
• "Diagnostic Potential of Differentially Expressed Homer1 and Homer2 in Ischemic Stroke. ". Cell Physiol Biochem. 2016. PMID 27832625.
• "Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning. ". Endocr Relat Cancer. 2011. PMID 21636702.
• "Recurrent microdeletions of 15q25.2 are associated with increased risk of congenital diaphragmatic hernia, cognitive deficits and possibly Diamond--Blackfan anaemia. ". J Med Genet. 2010. PMID 20921022.
• "Replicated genetic evidence supports a role for HOMER2 in schizophrenia.". Neurosci Lett. 2010. PMID 19914345.