HK1

HK1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CZA, 1DGK, 1HKB, 1HKC, 1QHA, 4F9O, 4FOE, 4FOI, 4FPA, 4FPB
Dynodwyr
Cyfenwau	HK1, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, hexokinase 1, HK, hexokinase, RP79, NEDVIBA
Dynodwyr allanol	OMIM: 142600 HomoloGene: 100530 GeneCards: HK1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • mannokinase activity • phosphotransferase activity, alcohol group as acceptor • kinase activity • glucose binding • catalytic activity • GO:0001948, GO:0016582 protein binding • fructokinase activity • ATP binding • glucokinase activity • hexokinase activity • peptidoglycan binding • identical protein binding Cydrannau o'r gell • cytosol • bilen • cilium • mitochondrial outer membrane • sperm principal piece • mitocondria • membrane raft Prosesau biolegol • glycolytic process • phosphorylation • canonical glycolysis • cellular glucose homeostasis • maintenance of protein location in mitochondrion • establishment of protein localization to mitochondrion • hexose metabolic process • metabolaeth • glucose 6-phosphate metabolic process • carbohydrate metabolic process • carbohydrate phosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3098	n/a
Ensembl	ENSG00000156515	n/a
UniProt	P19367	n/a
RefSeq (mRNA)	NM_000188 NM_033496 NM_033497 NM_033498 NM_033500 NM_001322364 NM_001322365 NM_001322366 NM_001322367 NM_001358263	n/a
RefSeq (protein)	NP_000179 NP_001309293 NP_001309294 NP_001309295 NP_001309296 NP_277031 NP_277032 NP_277033 NP_277035 NP_001345192	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HK1 yw HK1 a elwir hefyd yn Phosphotransferase a Hexokinase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10q22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HK1.

• HK
• HKD
• HKI
• HXK1
• RP79
• HMSNR
• HK1-ta
• HK1-tb
• HK1-tc
• hexokinase

Llyfryddiaeth

• "HSMNR belongs to the most frequent types of hereditary neuropathy in the Czech Republic and is twice more frequent than HMSNL. ". Clin Genet. 2016. PMID 26822750.
• "Overexpression of Hexokinase 1 as a poor prognosticator in human colorectal cancer. ". Tumour Biol. 2016. PMID 26476538.
• "Identification of a Novel Gene on 10q22.1 Causing Autosomal Dominant Retinitis Pigmentosa (adRP). ". Adv Exp Med Biol. 2016. PMID 26427411.
• "A missense mutation in HK1 leads to autosomal dominant retinitis pigmentosa. ". Invest Ophthalmol Vis Sci. 2014. PMID 25316723.
• "A dominant mutation in hexokinase 1 (HK1) causes retinitis pigmentosa.". Invest Ophthalmol Vis Sci. 2014. PMID 25190649.