GSC

GSC
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DMU
Dynodwyr
Cyfenwau	GSC, SAMS, goosecoid homeobox
Dynodwyr allanol	OMIM: 138890 HomoloGene: 7744 GeneCards: GSC
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • sequence-specific DNA binding • DNA binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • transcription regulator complex • cnewyllyn cell • nuclear body Prosesau biolegol • embryonic skeletal system morphogenesis • multicellular organism development • neural crest cell fate specification • negative regulation of Wnt signaling pathway • forebrain development • dorsal/ventral neural tube patterning • anatomical structure morphogenesis • signal transduction involved in regulation of gene expression • ear development • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • gastrulation • muscle organ morphogenesis • middle ear morphogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	145258	n/a
Ensembl	ENSG00000133937	n/a
UniProt	P56915	n/a
RefSeq (mRNA)	NM_173849	n/a
RefSeq (protein)	NP_776248	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn GSC yw GSC a elwir hefyd yn Goosecoid homeobox (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q32.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GSC.

• SAMS

Llyfryddiaeth

• "Pedigree and genetic study of a bilateral congenital microtia family. ". Plast Reconstr Surg. 2010. PMID 20195123.
• "EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression. ". Dev Biol. 2012. PMID 22178155.
• "Goosecoid promotes the metastasis of hepatocellular carcinoma by modulating the epithelial-mesenchymal transition. ". PLoS One. 2014. PMID 25343336.
• "Overexpression of goosecoid homeobox is associated with chemoresistance and poor prognosis in ovarian carcinoma. ". Oncol Rep. 2014. PMID 24858567.
• "Chronic ethanol exposure increases goosecoid (GSC) expression in human embryonic carcinoma cell differentiation.". J Appl Toxicol. 2014. PMID 23378141.