FCER2

FCER2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4KI1, 1T8C, 1T8D, 2H2R, 2H2T, 4EZM, 4G96, 4G9A, 4GI0, 4GJ0, 4GJX, 4GK1, 4GKO, 4J6J, 4J6K, 4J6L, 4J6M, 4J6N, 4J6P, 4J6Q
Dynodwyr
Cyfenwau	FCER2, BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF, Fc fragment of IgE receptor II, FCErII, Fc epsilon receptor II
Dynodwyr allanol	OMIM: 151445 HomoloGene: 1517 GeneCards: FCER2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • IgE binding • integrin binding • GO:0001948, GO:0016582 protein binding • metal ion binding • carbohydrate binding Cydrannau o'r gell • integral component of membrane • extracellular region • Cellbilen • integral component of plasma membrane • extracellular exosome • external side of plasma membrane • bilen Prosesau biolegol • Notch signaling pathway • positive regulation of humoral immune response mediated by circulating immunoglobulin • positive regulation of nitric-oxide synthase activity • positive regulation of killing of cells of other organism • positive regulation of nitric-oxide synthase biosynthetic process • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2208	n/a
Ensembl	ENSG00000104921	n/a
UniProt	P06734	n/a
RefSeq (mRNA)	NM_001207019 NM_001220500 NM_002002	n/a
RefSeq (protein)	NP_001193948 NP_001207429 NP_001993	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FCER2 yw FCER2 a elwir hefyd yn Fc fragment of IgE receptor II (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FCER2.

• CD23
• FCE2
• CD23A
• IGEBF
• CLEC4J
• BLAST-2

Llyfryddiaeth

• "CTLA4Fcε, a novel soluble fusion protein that binds B7 molecules and the IgE receptors, and reduces human in vitro soluble CD23 production and lymphocyte proliferation. ". Immunology. 2016. PMID 26801967.
• "Protective Profile Involving CD23/IgE-mediated NO Release is a Hallmark of Cutaneous Leishmaniasis Patients from the Xakriabá Indigenous Community in Minas Gerais, Brazil. ". Scand J Immunol. 2015. PMID 25802003.
• "Genetic variations of the FCER2 gene and asthma susceptibility in north Indian children: a case-control study. ". Biomarkers. 2013. PMID 24102092.
• "FCER2 (CD23) asthma-related single nucleotide polymorphisms yields increased IgE binding and Egr-1 expression in human B cells. ". Am J Respir Cell Mol Biol. 2014. PMID 24010859.
• "Conformational plasticity at the IgE-binding site of the B-cell receptor CD23.". Mol Immunol. 2013. PMID 23933509.