EPB41L3

EPB41L3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2HE7, 3BIN
Dynodwyr
Cyfenwau	EPB41L3, 4.1B, DAL-1, DAL1, erythrocyte membrane protein band 4.1 like 3
Dynodwyr allanol	OMIM: 605331 HomoloGene: 49308 GeneCards: EPB41L3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • structural molecule activity • cytoskeletal protein binding • structural constituent of cytoskeleton • GO:0001948, GO:0016582 protein binding • actin binding Cydrannau o'r gell • cytoplasm • bilen • cell junction • juxtaparanode region of axon • paranode region of axon • axolemma • cell-cell junction • cytosol • Cytosgerbwd • Cellbilen • GO:0097483, GO:0097481 postsynaptic density Prosesau biolegol • GO:0097285 apoptotic process • cortical cytoskeleton organization • cytoskeleton organization • regulation of cell growth • GO:0033109 cortical actin cytoskeleton organization • paranodal junction assembly • myelin maintenance • protein localization to juxtaparanode region of axon • neuron projection morphogenesis • protein localization to plasma membrane • regulation of cell shape • protein localization to paranode region of axon • actomyosin structure organization • GO:0022610 proses fiolegol Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23136	n/a
Ensembl	ENSG00000082397	n/a
UniProt	Q9Y2J2	n/a
RefSeq (mRNA)	NM_001281533 NM_001281534 NM_001281535 NM_012307 NM_001330557	n/a
RefSeq (protein)	NP_001268462 NP_001268463 NP_001268464 NP_001317486 NP_036439	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EPB41L3 yw EPB41L3 a elwir hefyd yn Band 4.1-like protein 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 18, band 18p11.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EPB41L3.

• 4.1B
• DAL1
• DAL-1

Llyfryddiaeth

• "DAL-1 attenuates epithelial-to mesenchymal transition in lung cancer. ". J Exp Clin Cancer Res. 2015. PMID 25609022.
• "Tumor suppressor role of protein 4.1B/DAL-1. ". Cell Mol Life Sci. 2014. PMID 25183197.
• "Knockout of 4.1B triggers malignant transformation in SV40T-immortalized mouse embryo fibroblast cells. ". Mol Carcinog. 2017. PMID 27312663.
• "Aberrant expression of the candidate tumor suppressor gene DAL-1 due to hypermethylation in gastric cancer. ". Sci Rep. 2016. PMID 26923709.
• "DAL-1/4.1B contributes to epithelial-mesenchymal transition via regulation of transforming growth factor-β in lung cancer cell lines.". Mol Med Rep. 2015. PMID 26300315.