DOCK9

DOCK9
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WG7, 2WM9, 2WMN, 2WMO
Dynodwyr
Cyfenwau	DOCK9, ZIZ1, ZIZIMIN1, Dock9, dedicator of cytokinesis 9
Dynodwyr allanol	OMIM: 607325 HomoloGene: 41026 GeneCards: DOCK9
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • guanyl-nucleotide exchange factor activity • cadherin binding Cydrannau o'r gell • cytosol • endomembrane system • bilen Prosesau biolegol • blood coagulation • small GTPase mediated signal transduction • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • GO:0022610 proses fiolegol Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23348	n/a
Ensembl	ENSG00000088387	n/a
UniProt	Q9BZ29	n/a
RefSeq (mRNA)	NM_001130048 NM_001130049 NM_001130050 NM_015296 NM_001318849 NM_001366676 NM_001366677 NM_001366678 NM_001366679 NM_001366680 NM_001366681 NM_001366682 NM_001366683 NM_001366684	n/a
RefSeq (protein)	NP_001123520 NP_001123521 NP_001123522 NP_001305778 NP_056111 NP_001353605 NP_001353606 NP_001353607 NP_001353608 NP_001353609 NP_001353610 NP_001353611 NP_001353612 NP_001353613	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DOCK9 yw DOCK9 a elwir hefyd yn Dedicator of cytokinesis 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 13, band 13q32.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DOCK9.

• ZIZ1
• ZIZIMIN1

Llyfryddiaeth

• "Function of the N-terminus of zizimin1: autoinhibition and membrane targeting. ". Biochem J. 2008. PMID 17935486.
• "Sequence variation in DOCK9 and heterogeneity in bipolar disorder. ". Psychiatr Genet. 2007. PMID 17728666.
• "Variant c.2262A>C in DOCK9 Leads to Exon Skipping in Keratoconus Family. ". Invest Ophthalmol Vis Sci. 2015. PMID 26641546.
• "Snapshots form a big picture of guanine nucleotide exchange. ". Sci Signal. 2009. PMID 19809089.
• "Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor.". Science. 2009. PMID 19745154.