CYP2D6

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Cytochrome P450 family 2 subfamily D member 6
Dynodwyr
Cyfenwauxenobiotic monooxygenaseCYP2D6cytochrome P450 2D6nonfunctional cytochrome P450 2D6cytochrome P450-DB1cytochrome P450family 2subfamily Dpolypeptide 6cytochrome P450family 2subfamily Dpolypeptide 7 pseudogene 2cytochrome P450subfamily IID (debrisoquinesparteineetc.-metabolizing)polypeptide 6cytochrome P450subfamily II (debrisoquinesparteineetc.-metabolising)polypeptide 7 pseudogene 2cholesterol 25-hydroxylasecytochrome P450subfamily IID (debrisoquinesparteineetc.-metabolizing)-like 1cytochrome P450subfamily IID (debrisoquinesparteineetc.-metabolising)polypeptide 8 pseudogene 2debrisoquine 4-hydroxylasecytochrome P450family 2subfamily Dpolypeptide 8 pseudogene 2flavoprotein-linked monooxygenasemicrosomal monooxygenaseCYPIID6
Dynodwyr allanolGeneCards: [1]
Patrwm RNA pattern
PBB GE CYP2D6 207498 s at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Lleoliad (UCSC)n/an/a
PubMed searchn/an/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYP2D6 yw CYP2D6 a elwir hefyd yn Cytochrome P450 family 2 subfamily D member 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q13.2.[1]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYP2D6.

  • CPD6
  • CYP2D
  • CYP2DL1
  • CYPIID6
  • P450C2D
  • P450DB1
  • CYP2D7AP
  • CYP2D7BP
  • CYP2D7P2
  • CYP2D8P2
  • P450-DB1

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Inference of the Genetic Polymorphisms of CYP2D6 in Six Subtribes of the Malaysian Orang Asli from Whole-Genome Sequencing Data. ". Genet Test Mol Biomarkers. 2017. PMID 28525288.
  • "Effect of 22 CYP2D6 variants found in the Chinese population on tolterodine metabolism in vitro. ". Chem Biol Interact. 2017. PMID 28087463.
  • "Significant Effect of Polymorphisms in CYP2D6on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study. ". Clin Cancer Res. 2017. PMID 27797974.
  • "Association between Functional CYP2D6 Polymorphisms and Susceptibility to Autoimmune Diseases: A Meta-Analysis. ". Immunol Invest. 2017. PMID 27749127.
  • "Influences of CYP2D6*10 polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis.". Acta Pharmacol Sin. 2016. PMID 27665849.

Cyfeiriadau[golygu | golygu cod y dudalen]