CST5

CST5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RN7, 1ROA
Dynodwyr
Cyfenwau	CST5, cystatin D
Dynodwyr allanol	OMIM: 123858 HomoloGene: 55615 GeneCards: CST5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidase inhibitor activity • GO:0001948, GO:0016582 protein binding • cysteine-type endopeptidase inhibitor activity • protease binding Cydrannau o'r gell • extracellular region • extracellular exosome • extracellular space Prosesau biolegol • negative regulation of peptidase activity • negative regulation of cysteine-type endopeptidase activity • negative regulation of endopeptidase activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1473	n/a
Ensembl	ENSG00000170367	n/a
UniProt	P28325	n/a
RefSeq (mRNA)	NM_001900	n/a
RefSeq (protein)	NP_001891	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CST5 yw CST5 a elwir hefyd yn Cystatin D (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20p11.21.

Llyfryddiaeth

• "Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression. ". J Biol Chem. 2015. PMID 26364852.
• "Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. ". J Clin Invest. 2009. PMID 19662683.
• "Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile. ". J Biol Chem. 2005. PMID 15728581.
• "A sequence variation in the human cystatin D gene resulting in an amino acid (Cys/Arg) polymorphism at the protein level. ". Hum Genet. 1993. PMID 8444475.
• "Localization of the human cystatin D gene (CST5) to chromosome 20p11.21 by in situ hybridization.". Cytogenet Cell Genet. 1993. PMID 8422752.