CFB

CFB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3HS0, 1DLE, 1Q0P, 1RRK, 1RS0, 1RTK, 2OK5, 2WIN, 2XWB, 2XWJ, 3HRZ
Dynodwyr
Cyfenwau	CFB, Cfb, AI195813, AI255840, Bf, C2, Fb, H2-Bf, AHUS4, ARMD14, BFD, CFAB, CFBD, FBI12, GBG, PBF2, complement factor B
Dynodwyr allanol	OMIM: 138470 HomoloGene: 1292 GeneCards: CFB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0070122 peptidase activity • serine-type peptidase activity • serine-type endopeptidase activity • hydrolase activity • complement binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • extracellular region • Cellbilen • blood microparticle • extracellular exosome • extracellular space Prosesau biolegol • complement activation • regulation of complement activation • proteolysis • immune system process • complement activation, alternative pathway • innate immune response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	629	n/a
Ensembl	ENSG00000243570 ENSG00000239754 ENSG00000243649 ENSG00000241253 ENSG00000242335 ENSG00000241534 ENSG00000204359	n/a
UniProt	P00751	n/a
RefSeq (mRNA)	NM_001710	n/a
RefSeq (protein)	NP_001701	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CFB yw CFB a elwir hefyd yn Complement factor B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p21.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CFB.

• BF
• FB
• BFD
• GBG
• CFAB
• CFBD
• PBF2
• AHUS4
• FBI12
• H2-Bf
• ARMD14

Llyfryddiaeth

• "Familial C3 glomerulonephritis associated with mutations in the gene for complement factor B. ". Nephrol Dial Transplant. 2015. PMID 25758434.
• "Complement factor B activation in patients with preeclampsia. ". J Reprod Immunol. 2015. PMID 25604034.
• "Association of the C2-CFB locus with non-infectious uveitis, specifically predisposed to Vogt-Koyanagi-Harada disease. ". Immunol Res. 2016. PMID 26671509.
• "BF*F allotype of the alternative pathway of complement: A marker of protection against the development of antiphospholipid antibodies in patients with systemic lupus erythematosus. ". Lupus. 2016. PMID 26537423.
• "The Relationship of Longitudinal Levels of Complement Bb During Pregnancy with Preeclampsia.". Am J Reprod Immunol. 2016. PMID 26510395.