CEBPB Dynodwyr Cyfenwau CEBPB Dynodwyr allanol OMIM: 189965 HomoloGene: 3807 GeneCards: CEBPB Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • protein homodimerization activity • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • transcription factor binding • histone deacetylase binding • chromatin binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • kinase binding • GO:0001948, GO:0016582 protein binding • histone acetyltransferase binding • ubiquitin-like protein ligase binding • protein heterodimerization activity • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • RNA polymerase II core promoter sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • glucocorticoid receptor binding Cydrannau o'r gell • cytoplasm • nuclear matrix • CHOP-C/EBP complex • nucleoplasm • cnewyllyn cell • condensed chromosome, centromeric region • RNA polymerase II transcription regulator complex Prosesau biolegol • GO:1904089 negative regulation of neuron apoptotic process • mammary gland epithelial cell proliferation • cell differentiation • GO:0009373 regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress • GO:1904579 cellular response to organic cyclic compound • embryonic placenta development • Cof • positive regulation of interleukin-4 production • response to endoplasmic reticulum stress • mammary gland epithelial cell differentiation • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • negative regulation of T cell proliferation • liver regeneration • positive regulation of osteoblast differentiation • hepatocyte proliferation • response to lipopolysaccharide • regulation of osteoclast differentiation • defense response to bacterium • acute-phase response • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • neuron differentiation • cellular response to interleukin-1 • brown fat cell differentiation • cellular response to amino acid stimulus • ovarian follicle development • liver development • inflammatory response • GO:0045996 negative regulation of transcription, DNA-templated • positive regulation of fat cell differentiation • cellular response to lipopolysaccharide • fat cell differentiation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress • transcription by RNA polymerase II • granuloma formation • T-helper 1 cell activation • GO:1901227 negative regulation of transcription by RNA polymerase II • regulation of odontoblast differentiation • positive regulation of biomineral tissue development • positive regulation of sodium-dependent phosphate transport • positive regulation of inflammatory response • positive regulation of cold-induced thermogenesis • regulation of dendritic cell differentiation Sources:Amigo / QuickGO
Orthologau Species Bod dynol Llygoden Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Lleoliad (UCSC) n/a n/a PubMed search[1] n/a Wicidata
Protein sy'n cael ei godio yn y corff dynol gan y genyn CEBPB yw CEBPB a elwir hefyd yn CCAAT/enhancer binding protein beta (Saesneg). Segment o DNA yw'r genyn , sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20q13.13.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CEBPB.
TCF5
IL6DBP
NF-IL6
C/EBP-beta
"The role of C/EBPβ phosphorylation in modulating membrane phospholipids repairing in LPS-induced human lung/bronchial epithelial cells. ". Gene . 2017. PMID 28760550 . "Exposure to p,p'-DDE Induces Morphological Changes and Activation of the PKCα-p38-C/EBPβPathway in Human Promyelocytic HL-60 Cells. ". Biomed Res Int . 2016. PMID 27833915 . "Staurosporine enhances ATRA-induced granulocytic differentiation in human leukemia U937 cells via the MEK/ERK signaling pathway. ". Oncol Rep . 2016. PMID 27665842 . "C/EBPβ-Thr217 Phosphorylation Stimulates Macrophage Inflammasome Activation and Liver Injury. ". Sci Rep . 2016. PMID 27067260 . "C/EBP β Mediates Endoplasmic Reticulum Stress Regulated Inflammatory Response and Extracellular Matrix Degradation in LPS-Stimulated Human Periodontal Ligament Cells. ". Int J Mol Sci . 2016. PMID 27011164 . 
