CASP6

CASP6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2WDP, 3K7E, 3NKF, 3NR2, 3OD5, 3P45, 3P4U, 3QNW, 3S70, 3S8E, 3V6L, 3V6M, 4EJF, 4FXO, 4HVA, 4IYR, 4N5D, 4N6G, 4N7J, 4N7M, 4NBK, 4NBL, 4NBN
Dynodwyr
Cyfenwau	CASP6, MCH2, Caspase 6, CSP-6
Dynodwyr allanol	OMIM: 601532 HomoloGene: 37455 GeneCards: CASP6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0070122 peptidase activity • cysteine-type endopeptidase activity • cysteine-type peptidase activity • endopeptidase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity • identical protein binding • cysteine-type endopeptidase activity involved in execution phase of apoptosis • cysteine-type endopeptidase activity involved in apoptotic process Cydrannau o'r gell • cytosol • nucleoplasm • cytoplasm Prosesau biolegol • epithelial cell differentiation • proteolysis • GO:0097285 apoptotic process • regulation of apoptotic process • execution phase of apoptosis • cellular response to staurosporine Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	839	n/a
Ensembl	ENSG00000138794	n/a
UniProt	P55212	n/a
RefSeq (mRNA)	NM_001226 NM_032992	n/a
RefSeq (protein)	NP_001217 NP_116787	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CASP6 yw CASP6 a elwir hefyd yn Caspase-6 a Caspase 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q25.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CASP6.

• MCH2

Llyfryddiaeth

• "Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency. ". Biochemistry. 2017. PMID 28726391.
• "Caspase-6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding. ". J Biol Chem. 2017. PMID 28154009.
• "Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment. ". Acta Neuropathol Commun. 2016. PMID 27931265.
• "The regulatory mechanism of the caspase 6 pro-domain revealed by crystal structure and biochemical assays. ". Acta Crystallogr D Biol Crystallogr. 2014. PMID 24419379.
• "Expression and activation of caspase-6 in human fetal and adult tissues.". PLoS One. 2013. PMID 24265764.