BAG4

BAG4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1M62, 1M7K
Dynodwyr
Cyfenwau	BAG4, BAG-4, SODD, BCL2 associated athanogene 4, BAG cochaperone 4
Dynodwyr allanol	OMIM: 603884 HomoloGene: 31270 GeneCards: BAG4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chaperone binding • ubiquitin protein ligase binding • GO:0001948, GO:0016582 protein binding • adenyl-nucleotide exchange factor activity • RNA binding Cydrannau o'r gell • cytoplasm • Cellbilen • cytosol • cnewyllyn cell Prosesau biolegol • positive regulation of peptidyl-serine phosphorylation • positive regulation of fibroblast migration • negative regulation of apoptotic process • negative regulation of protein targeting to mitochondrion • cellular response to epidermal growth factor stimulus • positive regulation of protein kinase B signaling • negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity • positive regulation of stress fiber assembly • protein folding • tumor necrosis factor-mediated signaling pathway • positive regulation of actin filament polymerization • protein localization to plasma membrane • ruffle assembly • positive regulation of cell adhesion • regulation of cellular response to heat • cellular response to tumor necrosis factor • negative regulation of mRNA modification • protein heterooligomerization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9530	n/a
Ensembl	ENSG00000156735	n/a
UniProt	O95429	n/a
RefSeq (mRNA)	NM_004874 NM_001204878	n/a
RefSeq (protein)	NP_001191807 NP_004865	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BAG4 yw BAG4 a elwir hefyd yn BCL2 associated athanogene 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8p11.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BAG4.

• SODD
• BAG-4

Llyfryddiaeth

• "BAG4/SODD protein contains a short BAG domain. ". J Biol Chem. 2002. PMID 12058034.
• "Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis. ". Curr Biol. 1999. PMID 10508612.
• "Silencer-of-Death Domain Mediates Acid-Induced Decrease in Cell Apoptosis in Barrett's Associated Esophageal Adenocarcinoma Cells. ". J Pharmacol Exp Ther. 2017. PMID 27756772.
• "Significance of SODD expression in childhood acute lymphoblastic leukemia and its influence on chemotherapy. ". Genet Mol Res. 2014. PMID 24737427.
• "[Effects of SODD and survivin on leukemia cell apoptosis induced by chemotherapeutic drugs].". Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007. PMID 17605853.