ARHGDIA

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ARHGDIA
Protein ARHGDIA PDB 1ajw.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauARHGDIA, GDIA1, HEL-S-47e, NPHS8, RHOGDI, RHOGDI-1, Rho GDP dissociation inhibitor alpha
Dynodwyr allanolOMIM: 601925 MGI: 2178103 HomoloGene: 908 GeneCards: ARHGDIA
Patrwm RNA pattern
PBB GE ARHGDIA 201167 x at fs.png

PBB GE ARHGDIA 213606 s at fs.png

PBB GE ARHGDIA 211716 x at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_133796
NM_001363425

RefSeq (protein)

NP_598557
NP_001350354

Lleoliad (UCSC)n/aChr : 120.58 – 120.58 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARHGDIA yw ARHGDIA a elwir hefyd yn Rho GDP-dissociation inhibitor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.3.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARHGDIA.

  • GDIA1
  • NPHS8
  • RHOGDI
  • RHOGDI-1
  • HEL-S-47e

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Proteome analysis of irradiated endothelial cells reveals persistent alteration in protein degradation and the RhoGDI and NO signalling pathways. ". Int J Radiat Biol. 2017. PMID 28697312.
  • "Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation. ". J Biol Chem. 2016. PMID 26719334.
  • "Loss of ARHGDIA expression is associated with poor prognosis in HCC and promotes invasion and metastasis of HCC cells. ". Int J Oncol. 2014. PMID 24859471.
  • "Overexpression of RhoGDI, a novel predictor of distant metastasis, promotes cell proliferation and migration in hepatocellular carcinoma. ". FEBS Lett. 2014. PMID 24374343.
  • "Loss of RhoGDI is a novel independent prognostic factor in hepatocellular carcinoma.". Int J Clin Exp Pathol. 2013. PMID 24228117.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. 1.0 1.1 1.2 GRCm38: Ensembl release 89: ENSMUSG00000025132 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. ARHGDIA - Cronfa NCBI