ALPP

ALPP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1EW2, 1ZEB, 1ZED, 1ZEF, 2GLQ, 3MK0, 3MK1, 3MK2
Dynodwyr
Cyfenwau	ALPP, ALP, PALP, PLAP, PLAP-1, alkaline phosphatase, placental, ALPI, IAP
Dynodwyr allanol	OMIM: 171800 HomoloGene: 122414 GeneCards: ALPP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • alkaline phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • zinc ion binding • GO:0001948, GO:0016582 protein binding • hydrolase activity • catalytic activity • magnesium ion binding • metal ion binding Cydrannau o'r gell • integral component of membrane • anchored component of membrane • cell surface • bilen • Cellbilen Prosesau biolegol • metabolaeth • GO:0098501, GO:0098502, GO:0006286 dephosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	250	n/a
Ensembl	ENSG00000163283	n/a
UniProt	P05187	n/a
RefSeq (mRNA)	NM_001632	n/a
RefSeq (protein)	NP_001623	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ALPP yw ALPP a elwir hefyd yn Alkaline phosphatase, placental (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q37.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ALPP.

• ALP
• PALP
• PLAP
• PLAP-1

Llyfryddiaeth

• "Catalytic activity of human placental alkaline phosphatase (PLAP): insights from a computational study. ". J Phys Chem B. 2014. PMID 25409280.
• "Polymorphisms of human placental alkaline phosphatase are associated with in vitro fertilization success and recurrent pregnancy loss. ". Am J Pathol. 2014. PMID 24296104.
• "A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer. ". MAbs. 2014. PMID 24247025.
• "High serum alkaline phosphatase cooperating with MMP-9 predicts metastasis and poor prognosis in patients with primary osteosarcoma in Southern China. ". World J Surg Oncol. 2012. PMID 22333159.
• "Computational modeling of the catalytic mechanism of human placental alkaline phosphatase (PLAP).". J Chem Inf Model. 2011. PMID 21939286.