CXADR

CXADR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1EAJ, 1F5W, 1JEW, 1KAC, 1P69, 1P6A, 1RSF, 2J12, 2J1K, 2NPL, 2W9L, 2WBW, 3J6L, 3J6M, 3J6N, 3J6O
Dynodwyr
Cyfenwau	CXADR, CAR, CAR4/6, HCAR, coxsackie virus and adenovirus receptor, Ig-like cell adhesion molecule, CXADR Ig-like cell adhesion molecule
Dynodwyr allanol	OMIM: 602621 HomoloGene: 1024 GeneCards: CXADR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • PDZ domain binding • beta-catenin binding • connexin binding • virus receptor activity • integrin binding • GO:0001948, GO:0016582 protein binding • identical protein binding • signaling receptor binding • cell adhesion molecule binding • cell adhesive protein binding involved in AV node cell-bundle of His cell communication Cydrannau o'r gell • cytoplasm • integral component of membrane • cell body • bilen • intercalated disc • cell-cell junction • bicellular tight junction • filopodium • growth cone • adherens junction • neuromuscular junction • Cellbilen • integral component of plasma membrane • nucleoplasm • extracellular region • cell junction • apicolateral plasma membrane • basolateral plasma membrane • acrosomal vesicle • membrane raft • neuron projection • extracellular space • GO:0009327 protein-containing complex Prosesau biolegol • actin cytoskeleton reorganization • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • cell-cell junction organization • epithelial structure maintenance • AV node cell to bundle of His cell communication • gamma-delta T cell activation • mitochondrion organization • neutrophil chemotaxis • transepithelial transport • homotypic cell-cell adhesion • heart development • cell adhesion • defense response to virus • regulation of immune response • viral entry into host cell • GO:0022415 viral process • leukocyte migration • germ cell migration • AV node cell-bundle of His cell adhesion involved in cell communication • regulation of AV node cell action potential • negative regulation of cardiac muscle cell proliferation • cell-cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1525	n/a
Ensembl	ENSG00000154639	n/a
UniProt	P78310	n/a
RefSeq (mRNA)	NM_001207063 NM_001207064 NM_001207065 NM_001207066 NM_001338	n/a
RefSeq (protein)	NP_001193992 NP_001193993 NP_001193994 NP_001193995 NP_001329	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CXADR yw CXADR a elwir hefyd yn CXADR, Ig-like cell adhesion molecule (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 21, band 21q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CXADR.

• CAR
• HCAR
• CAR4/6

Llyfryddiaeth

• "Loss of coxsackie and adenovirus receptor expression in human colorectal cancer: A potential impact on the efficacy of adenovirus-mediated gene therapy in Chinese Han population. ". Mol Med Rep. 2016. PMID 27485384.
• "The Coxsackievirus and Adenovirus Receptor: Glycosylation and the Extracellular D2 Domain Are Not Required for Coxsackievirus B3 Infection. ". J Virol. 2016. PMID 27030267.
• "Membrane Dynamics and Signaling of the Coxsackievirus and Adenovirus Receptor. ". Int Rev Cell Mol Biol. 2016. PMID 26940522.
• "Human adenovirus 52 uses sialic acid-containing glycoproteins and the coxsackie and adenovirus receptor for binding to target cells. ". PLoS Pathog. 2015. PMID 25674795.
• "Coxsackie and adenovirus receptor is increased in adipose tissue of obese subjects: a role for adenovirus infection?". J Clin Endocrinol Metab. 2015. PMID 25459915.