CTSZ

CTSZ
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1DEU, 1EF7
Dynodwyr
Cyfenwau	CTSZ, CTSX, cathepsin Z
Dynodwyr allanol	OMIM: 603169 HomoloGene: 1022 GeneCards: CTSZ
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • GO:0070122 peptidase activity • hydrolase activity • cysteine-type endopeptidase activity • cysteine-type peptidase activity • carboxypeptidase activity Cydrannau o'r gell • endoplasmic reticulum lumen • COPII-coated ER to Golgi transport vesicle • intracellular membrane-bounded organelle • Reticwlwm endoplasmig • Cellbilen • endoplasmic reticulum-Golgi intermediate compartment membrane • extracellular exosome • Golgi membrane • extracellular region • specific granule lumen • ficolin-1-rich granule lumen • extracellular space • lysosome • cell surface • growth cone • GO:0016023 cytoplasmic vesicle • cell cortex region • collagen-containing extracellular matrix Prosesau biolegol • proteolysis involved in cellular protein catabolic process • COPII vesicle coating • endoplasmic reticulum to Golgi vesicle-mediated transport • epithelial tube branching involved in lung morphogenesis • angiotensin maturation • neutrophil degranulation • proteolysis • negative regulation of plasminogen activation • negative regulation of neuron projection development • negative regulation of protein binding • positive regulation of neuron apoptotic process • regulation of neuron death • positive regulation of neural precursor cell proliferation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1522	n/a
Ensembl	ENSG00000101160	n/a
UniProt	Q9UBR2	n/a
RefSeq (mRNA)	NM_001336	n/a
RefSeq (protein)	NP_001327	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CTSZ yw CTSZ a elwir hefyd yn Cathepsin Z (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20q13.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CTSZ.

• CTSX

Llyfryddiaeth

• "Characterization of cathepsin X in colorectal cancer development and progression. ". Pathol Res Pract. 2014. PMID 25442015.
• "Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients. ". BMC Cancer. 2014. PMID 24725597.
• "Cellular senescence induced by cathepsin X downregulation. ". Eur J Cell Biol. 2011. PMID 21616554.
• "Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study. ". Hum Immunol. 2011. PMID 21354459.
• "RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties.". J Biol Chem. 2006. PMID 17065156.